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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC1
All Species:
5.45
Human Site:
S373
Identified Species:
13.33
UniProt:
Q12948
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12948
NP_001444.2
553
56789
S373
S
Q
T
S
S
A
G
S
S
G
G
G
G
G
G
Chimpanzee
Pan troglodytes
XP_001174718
240
23092
T79
G
G
A
G
G
A
G
T
Y
H
C
N
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001119000
442
46184
R281
P
G
S
L
P
S
A
R
P
L
S
L
D
G
A
Dog
Lupus familis
XP_546791
479
51548
C317
P
A
A
Y
G
Q
P
C
A
Q
G
L
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61572
553
56935
S373
S
Q
S
S
S
A
G
S
S
G
G
G
G
G
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990337
528
54812
A336
S
P
C
G
Q
P
A
A
A
A
A
G
S
Y
H
Frog
Xenopus laevis
Q9PVZ3
492
53656
I327
I
S
S
S
R
T
G
I
A
P
S
L
S
L
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
G325
A
H
P
L
T
P
G
G
Q
G
A
G
G
Q
S
Honey Bee
Apis mellifera
XP_001121752
495
55049
N324
A
A
L
M
T
R
E
N
Q
H
H
T
H
H
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
P342
R
T
G
Q
L
L
S
P
Q
P
L
G
Y
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
79.1
50.2
N.A.
93.4
N.A.
N.A.
N.A.
57.3
69.9
N.A.
N.A.
32.3
31.1
N.A.
35
Protein Similarity:
100
43.2
79.3
60.7
N.A.
95.1
N.A.
N.A.
N.A.
62.5
75.5
N.A.
N.A.
43.2
42.5
N.A.
48.6
P-Site Identity:
100
13.3
6.6
13.3
N.A.
93.3
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
26.6
0
N.A.
6.6
P-Site Similarity:
100
20
20
20
N.A.
100
N.A.
N.A.
N.A.
26.6
26.6
N.A.
N.A.
40
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
20
0
0
30
20
10
30
10
20
0
0
10
20
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
10
20
20
0
50
10
0
30
30
50
30
30
30
% G
% His:
0
10
0
0
0
0
0
0
0
20
10
0
10
10
10
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
20
10
10
0
0
0
10
10
30
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
20
10
10
0
10
20
10
10
10
20
0
0
0
0
20
% P
% Gln:
0
20
0
10
10
10
0
0
30
10
0
0
0
20
0
% Q
% Arg:
10
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
30
10
30
30
20
10
10
20
20
0
20
0
20
10
20
% S
% Thr:
0
10
10
0
20
10
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _